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Aspirin Anti-Clotting Effect Weakens Over Time

The March 17, 2004 Journal of the American College of Cardiology reports that over time, aspirin taken daily to prevent blood clotting loses its effectiveness.

Previous research has indicated that aspirin’s clinical efficacy decreases over a two year period. This study, done at the University “La Sapienza” in Rome, Italy also found similar results after monitoring blood samples from 150 patients for two years after they started aspirin therapy.

At the beginning of treatment, a maximum of 88% of patient’s platelets could be made to clump together. While aspirin therapy decreased that number to 38% after two months, the clumping gradually increased back up to 62% after 24 months.

Previous research has also shown that while people taking an aspirin a day do experience a lower incidence of heart episodes, they suffer from a higher incidence of stroke and kidney disease than those who don’t take a daily aspirin.

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